Endocrine Abstracts

The obesity epidemic, which has persisted for more than 45 years, is now being faced concurrently with the coronavirus pandemic, with deadly effects. The complex changes caused by obesity, such as chronic inflammation, are known to be detrimental in patients with COVID-19. 33.2% of the Georgian population is obese (1). Therefore, we aimed to explore the synergistic effects between obesity and SARS-CoV-2. The objective of our study is to compare the presence of neutralizing ant...

Introduction: Childhood obesity has reached epidemic levels in developed as well as in developing countries. According to WHO data, an increasing number of low- and middle-income countries are now facing the "double burden" of obesity and overweightness. This problem is increasing aggressively in urban settings. This rise has occurred similarly among boys and girls. In 2016, 18% of girls and 19% of boys were overweight. In comparison, two data illustrate the pandemic s...

The ketogenic diet (KD) has been extensively studied as a potential therapeutic approach for various conditions, including Polycystic Ovary Syndrome (PCOS) in women. We describe a 29-year-old overweight woman with PCOS. Clinically, she presented with hirsutism, acne, and pink stretch marks in the hip and abdomen areas, no significant menstrual cycle disturbances were reported. Patient underwent a 12-week KD regimen. Initially, her body mass index (BMI) was 33.5, with a weight ...

The therapy of hyperprolactinemia with dopamine agonists (DAs) is highly effective in the majority of cases (1). However, some patients fail to achieve normal prolactin levels and develop drug resistance towards prescribed medicine. This case study describes a medical history of The Georgian National Institute of Endocrinology patient, with a drug-resistant hyperprolactinemia and inability to conceive. The patient’s MRI scan result has not indicated incidence of pr...

Introduction: Puberty is a crucial period, marking the transition from childhood to adulthood with significant physical and psychological changes. (1) In girls, when puberty begins before the age of eight, it is considered precocious. (2) While multiple factors influence individual differences in pubertal timing, the interactions between hormones and nutrition during critical growth periods, like puberty, are crucial. (3) Girls with a higher BMI experienced early menarche comp...